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Considerations for resting state functional MRI and functional connectivity studies in rodents

Starting at low doses (0.25 mg) and titrating gradually minimizes gastrointestinal distress

Some see an effect within minutes, and others may take up to 2 hours after injection

This can be related to reduced calorie intake, changes in blood sugar regulation, or general metabolic adjustment

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Methylcobalamin is the active and naturally occurring form of Vitamin B12, which is critical for the healthy function of the brain, nerves, and for the formation of red blood cells