The copper ion within the complex is integral to its antioxidant and anti-inflammatory activities
Western blot analysis showed that inhibition of EPAC resulted in downregulation of cyclins E1, A2, and B1 and cell cycle dependent kinases CDK4 and CDK2, and concomitant upregulation of cell cycle inhibitors p16, p21, and p27 (Fig
they're slow and cumulative actives and not overnight fixers
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This is because of its exceptional antioxidant potency, ie, its ability to combat damage caused by oxidative stress