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Furthermore, tricyclic antidepressants were riskier than selective serotonin-reuptake inhibitors (SSRIs)

Nausea The most commonly reported side effect

Cargill found that only 26% of GLP-1 RA users intend to never stop using these drugs, noted Barhoover

However, when the investigational drug presents a higher level of risk for example in certain oncology settings, where the compound may be too toxic for healthy subjects the study may involve patients instead