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In November 2025, Brazilian courts denied a request from Novo Nordisk to extend the medical patent for 5 years

Clinical takeaway: For stable CAD patients requiring full-dose anticoagulation, routine aspirin use offers no net benefit and increases harm

Significant water absorption goes paracellular in kidney proximal tubules

Results Fragment-based drug design and chemistry Utilizing actives identified in a quantitative high-throughput screen against Schistosoma mansoni TGR 20,35 , 92 commercially available low molecular weight (MW) compounds/fragments were tested by X-ray crystallography 33,34,36

Peterson adds that hes thankful to see GLP-1 agonist drugs becoming more accessible

Trends Neurosci 33 : 103109