The combination has a very low risk of hypoglycaemia because both medications work in glucose-dependent ways
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Additionally, keeping regular check-ins with a healthcare provider can help identify any significant changes in weight, appetite, or energy levels early on, allowing for adjustments to the treatment plan if needed
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They also support immune function, reducing infection risk and supporting the body's ability to manage surgical stress
therefore, to compare semaglutide with other active comparators, indirect treatment comparison is required