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Similarly, in the kidneys, lipid accumulation disrupts podocyte function and induces inflammation through toll-like receptor 4 (TLR4)-NF-B activation, exacerbating glomerular damage and chronic kidney disease (57)

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Biomarker Development : There is a need for valid biomarkers of lipid peroxidation and ferroptosis for patient characterization as well as ferritin assays monitoring

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The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin

If a P -value of the Egger test was less than 0.05, additional analysis was conducted after excluding the studies that caused asymmetry in the funnel plot