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There are currently no approved orally-administered GLP-1 agonists on the market for the treatment of obesity, said Jesper Hiland, Senior Strategic Advisor for Rani Therapeutics and former executive at Novo Nordisk

The benzyl alcohol preservative allows multi-dose use, meaning a single vial can be accessed multiple times over several weeks using sterile technique

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Resting Energy Expenditure Small-scale indirect calorimetry studies suggest tirzepatide modestly increases resting energy expenditure (REE) beyond what weight loss alone predicts, an effect not consistently seen with liraglutide or semaglutide at approved doses

It can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, constipation, abdominal discomfort, and reflux

Durability Most IV Therapy treatments are given once a week for four weeks to build up their levels