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A 1-year randomized controlled trial in 130 Alzheimer's patients found that ALCAR treatment (dosage not specified in abstract) resulted in slower rates of deterioration across 13 of 14 outcome measures, with statistical significance achieved for memory, intelligence, attention, and functional scales

For the microneedle fabrication, PLGA (2000 mg/mL) was dissolved in dimethylformamide and mixed with metformin

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A casecontrol study suggested that smoking may be a significant risk factor for idiopathic congestive cardiomyopathy, with the risk doubling for every 39 pack-years of smoking history [25]