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Current Knowledge and Pharmacological Profile of Berberine: An Update

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2023): Nevertheless, literature on COMT-I is controversial and other studies have not yielded similar beneficial effects (Uncini et al

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For example, cis-3-(9H-purin-6-ylthio)acrylic acid (PTA) is a prodrug of the antitumor and immunosuppressive antimetabolite 6-mercaptopurine that requires GSH conjugation and subsequent metabolism for activation (Gunnarsdottir and Elfarra, 1999)

Immune Support: Strengthens the immune system