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4E) are depleted by log 2 = 0.27 and log 2 = 0.42 in Ms4a15 OE cells treated with RSL3 (Fig

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A detailed description of those events for the various types of TBI can be found in the published literature and will not be repeated in this document

We hypothesize that SAC inhibits the E3 ubiquitin ligase activity of KEAP1 through interaction, thereby blocking the ubiquitination-mediated degradation of NRF2, stabilizing the NRF2 protein, and activating the transcription of various protective genes, including antioxidant enzymes

Regulation of TGF- family signaling by inhibitory smads