Quick Reference: Standard Protocol Community-documented protocol: 1 mg subcutaneous in the morning, 5 days on / 2 days off, for 2-week courses repeated 2-3 times per year, with 3-6 months rest between courses
Hydroxocobalamin This form is naturally created by bacteria fermentation and is the main type that is found in food
PCS, p-cresol sulfate
Kee and Hong also investigated these effects, confirming arctigenin (2, 10, and 50 M) reductions on histamine, RNA expression of chemokines macrophage inflammatory protein (MIP)-1, MIP-1, macrophage inflammatory protein (MCP-1), and Regulated Upon Activation, Normally T-Expressed, And Presumably Secreted (RANTES) and pro-inflammatory cytokines, including IL-1, IL-6, IL-8, and TNF-, and protein expression of p-ERK/ERK, p-JNK/JNK, p-p38/p38 and NFB phosphorylation in HMC-1 mast cells [85]
If your concentration is 5mg/mL (5000mcg/mL), that same 250mcg dose requires only 0.05mL
Image: Beyens A, Pottie L, Sips P, Callewaert B