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Not yet as an approved therapy

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To investigate whether the gut microbiome and its metabolites contribute to statin-associated glucose intolerance, we recruited 30 patients with atorvastatin and 10 controls, followed up for 16 weeks, and found a decreased abundance of the genus Clostridium in feces and altered serum and fecal bile acid profiles among patients with atorvastatin therapy

To view a copy of this licence, visit About this article Cite this article Godlewska, B.R., Sylvester, A.L., Emir, U.E

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On the third day, mice got two 0.15% saccharin (98+%, Thermo Fisher Scientific Chemicals, 149001000) bottles for 1 hour and were immediately injected or orally gavaged with vehicle or drug (LiCl (125 mg kg 1 ), danuglipron (30 mg kg 1 ), liraglutide (0.3 mg kg 1 ) or orforglipron (1 mg kg 1 ))