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They also have some effects in the brain to decrease hunger. If youve struggled to manage your weight, you may be wondering if youre a candidate for GLP-1 medications

Diarrhoea, abdominal pain, and reduced appetite are also commonly reported, reflecting the medication's effect on gastrointestinal motility and gastric emptying

Molecules 23 (10), 2592

When you block this pathway, you reduce its suppressive effect on skeletal muscle tissue

Some people begin to notice mild headaches or water retention at this level

In a 48-week study involving adults with obesity, participants receiving the highest weekly dose achieved an average body weight reduction of up to 24.2%