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People living with HIV often show epigenetic aging patterns years ahead of their chronological age, a phenomenon researchers believe is driven by persistent immune activation and chronic inflammation, even when viral loads are well-controlled by antiretroviral therapy

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Acknowledgements The authors extend their gratitude to Birla Institute of Technology and Science, Pilani (BITS Pilani), Pilani Campus, for providing the necessary facilities for writing this review

Propionate (PA) reduces intestinal cholesterol absorption and lowers plasma LDL cholesterol via immune mechanisms, increasing regulatory T cells and IL-10 while inhibiting Npc1l1 expression

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