It is vital to mitochondrial function and necessary to produce DNA
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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice Nature Medicine 2017;23(1):107-113 doi:10.1038/nm.4236 (Animal study) Depommier C, Everard A, Druart C, et al
Lippi G, Montagnana M, Salvagno GL, Guidi GC, Targher G (2008) Prevalence of folic acid and vitamin B 12 deficiencies in patients with thyroid disorders
International Journal of Obesity , 33(9), 956961
Uniprot P36969-2) is constituted by a catalytic tetrad that consists of the following residues: selenocysteine (Sec 46 ), glutamine (Gln 81 ), tryptophan (Trp 136 ) and asparagine (Asn 137 ) [35]