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Research suggests that GLP-1 agonists may reduce the hedonic or reward-driven aspects of eating, not merely physiological hunger

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Luoqian J, Yang W, Ding X, Tuo QZ, Xiang Z, Zheng Z, et al

In line with preclinical research, we find that ghrelin increases reward responses across studies in key nodes of the motivational circuit, such as the nucleus accumbens, pallidum, putamen, substantia nigra, ventral tegmental area, and the dorsal mid insula

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