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That remained the case for nearly two decades
Other digestive issues include: Diarrhea or loose stools Constipation Stomach pain or discomfort Vomiting Reduced appetite (which contributes to weight loss) Heartburn or acid reflux Most of these side effects feel strongest during the first month and gradually decrease over time
history of previous nutrient deficiency
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The programme also included a long-term safety trial, trials to evaluate the use of orally administered semaglutide in individuals with moderate renal impairment and as add-on to insulin as well as a cardiovascular outcome trial (CVOT) to evaluate the CV safety profile
The peptide is given by injection just under the skin
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