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Can.J Public Health 2008;99(4):276-280

This provides more space to accommodate the B-ring of bicalutamide, allowing the AR to maintain a similar fold as that seen in other agonist-bound structures and thus favoring the formation of an active state of AF2

They target different areas and complement each other

"People who drink know there's a difference between nursing a glass of wine and downing a shot of whiskey," researcher Alex DiFeliceantonio said in a news release

CEO has also been shown to mimic superoxide dismutase activity, as evidenced by its ability to inhibit pyrogallol autoxidation [81, 82]

PMCID: PMC6276298.