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GLP-1 acts on those receptors in the brain and it results in the patients having decreased appetite and decreased hunger," explains Dr Sukhvinder Singh Saggu, Director Minimal Access, GI & Bariatric Surgery at the CK Birla Hospital, Delhi

doi: 10.2174/0929867327666200212100644

This dual approach addresses both sides of the energy balance equation, explaining the unprecedented 24% weight loss achieved in clinical trialssignificantly exceeding the 15-20% typically achieved with appetite suppression alone

Notably, laboratory self-administration results also suggested no medication effects on delay time or abstinence (eResults in Supplement 2)

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However, evidence also suggests BCAAs may possess neuroprotective properties by supporting neuronal energy metabolism and protein synthesis to maintain neuronal function