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P21 is an adamantane-containing synthetic peptide mimetic derived from Ciliary Neurotrophic Factor (CNTF) that operates via CNTF/JAK-STAT pathways

In addition to functioning as a purification tag, GST acts as a chaperone for the attached protein, promoting its correct folding, as well as preventing it from becoming aggregated in inclusion bodies when expressed in bacteria

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The TGF-beta1 suppression finding provides a plausible mechanism for follicle growth extension (Pyo et al., 2007)

Am J Physiol Cell Physiol

But stress, aging, hormones, inflammation, poor nutrition, and environmental damage can interfere with this natural process