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These concentrations are 100 to 1000 times lower than concentrations observed in other studies after infants received oxycodone at 0.1 mg/kg/dose (~20-200 ng/mL)

Glutathione plays a critical role in protecting the body from oxidative stress and supporting cellular health

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Additionally, HO-1-derived BL and CO have been shown to upregulate brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression in both neurons and astrocytes, thereby facilitating proper DA neuron development (Hung et al., 2010)

Gonzalez-Reyes RE, Aliev G, Avila-Rodrigues M, Barreto GE