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Neurons undergoing ferroptosis release damage-associated molecular patterns (DAMPs) such as high-mobility group box-1 protein (HMGB1), ATP, and exosomes enriched in ACSL4-derived metabolites

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Allen & Bradley (2011, Alternative Medicine Review): comprehensive review documenting glutathiones role in detoxification of heavy metals and environmental toxins, noting that depleted glutathione levels are consistently associated with increased disease susceptibility