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The bioavailability of the two on demand formulations are very different

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Cow or sheep liver:Sheep, containing more than 1% of vitamin B12

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it protects tissue from further damage by modulating the inflammatory cascade systemically

Fourteen genes whose expression is significantly correlated with regional emphysema severity or transcription factors that are highly connected to these genes in the relevance network were selected for quantitative RT-PCR validation in a subset of tissue cores from subjects with severe emphysema (see Additional file 1 for methods)