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Future research should focus on improving study quality, standardizing methodologies, the adoption of a standard outcome measure, and expanding representation to improve our understanding of the efficacy and safety of AOMs in this region

They work by mimicking a natural hormone called GLP-1, which helps regulate blood sugar levels and appetite

Interestingly, L585 could only be replaced with an amino acid having similar physiochemical properties, including isoleucine, methionine, and valine, without negatively affecting FcRn binding 64

GLP-1 receptor agonists enhance regulatory T cell function

It should be noted that the cerebral cortex and the cerebellum interestingly lack the expression of the GLP-1R in rat models [51]

New Research Links GLP-1 Agonists to NAION A study published in JAMA Ophthalmology on July 3, 2024, found that type 2 diabetes patients prescribed GLP-1 agonists were at an increased risk for developing a rare and debilitating eye condition called NAION