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A previous study revealed that genistein can enhance the AMPK signaling pathway and SIRT1 activity through GPER activation, subsequently inhibiting the expression of genes associated with hepatic lipogenesis and further influencing liver metabolic status [169]

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New York-based Oramed is currently conducting a phase 1 trial of its oral GLP-1 drug ORMD-0901 as a treatment for type 2 diabetes

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