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Molecular Metabolism (2018) 12

These include: Nausea (affecting 20-40% of patients initially) Vomiting Diarrhoea Constipation Abdominal discomfort These symptoms can be debilitating during the first few weeks of treatment and may cause fatigue, reduced appetite, and general malaise

In the UK, semaglutide (Wegovy) is approved for weight management under NICE guidance

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Ive had one patient develop severe panic attacks that resolved when we discontinued the medication