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In addition to GLP-1 RA monoagonists (eg, semaglutide), dual incretin receptor agonists targeting GLP-1R and glucose-insulinotropic polypeptide receptors (GIP) (eg, tirzepatide) are now available, with anticipated approval of triple agonists (eg, retatrutide

A., Mocan, A., Echeverra, J., Pop, R

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Somatostatin release also occurred in the dorsal dentate gyrus in rats subjected to immobilization (Arancibia et al., 2 mRNA was upregulated following acute exposure of rats to a potential predator (Nanda et al., 2008), a finding recently also observed in the medial habenula following chronic mild stress (Faron-Gorecka et al., 2016)

Hu C (2025) Prevention of cardiovascular disease for healthy aging and longevity: a new scoring system and related mechanisms-hallmarks-biomarkers. Ageing Res Rev 107:102727