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You need to use it regularly (at least 23 months) to see results

Providers can discuss options you may not have considered, including split dosing protocols, combination approaches involving metformin or phentermine as adjuncts, dose timing optimization, or even switching to a medication with a longer half-life that provides more consistent weekly coverage

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doi: 10.1016/j.amjmed.2011.10.008 24 PrattesJ.KoidlC.EiglS.KrauseR.HoeniglM

And, brands like Zepbound are FDA approved for chronic weight management