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Briefly, HL-1 and H9C2 cells were treated for 24 h with a range of PQQ concentrations (1200 M), after which a CCK-8 assay was used to examine cell viability

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The production of inflammatory cytokines such as TNF- , IL-1, and IL-6 is provoked by ROS production (Asami and Shimizu 2021)

Pernicious anemia is associated with an increased incidence of carcinoma of the stomach, but this is believed to be related to the underlying pathology and not to treatment with cyanocobalamin