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Tirzepatide can also help with weight management in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes or high cholesterol) for use, in addition to a reduced-calorie diet and increased physical activity

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Short-acting GLP-1 agents like exenatide immediate-release (Byetta) and lixisenatide (Adlyxin) must be administered within 60 minutes before meals