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The overexpression of arginine methyltransferase 5 (PRMT5) in solid and hematological tumors leads to the elevation of the methylation level of arginine residues on functionally related proteins in tumor cells, which affects cell cycle regulation, mRNA splicing, cell differentiation, signal transduction, and other physiological processes

Pak J Med Sci

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DSIP wordt voornamelijk onderzocht in preklinische en experimentele studies

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For example, lower educational attainment in women than in men born in the first half of the 20th century may contribute to elevated risk in women, as limited formal education is a risk factor for dementia