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In contrast, PWA mice display overt metabolic perturbations, including overweight and impaired glucose homeostasis 46 , and may mimic the canonical human phenotype A of PCOS linked to hyperandrogenism, anovulatory cycles, and polycystic ovarian morphology 45

The main concern is that persistent nausea, vomiting, or diarrhea may cause dehydration and reduced kidney perfusion

The safety profile was largely in line with established GLP-1based therapies, with gastrointestinal events being the most common and generally manageable

Key highlights: GLP-1 Activators naturally help the body increase GLP-1 levels, improving hunger control, energy, and blood sugar balance

TRIUMPH-4 has already delivered positive topline results