93 In their model, cydD mutants had reduced trimethoprim uptake, which was reversed by deleting acrAB or by restoring GSH (74)
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This decline may result in higher levels of oxidative stress, Free radicals can harm cells and exacerbate several illnesses.
Both receptors share a typical structure consisting of a carboxy-terminal ligand-binding domain, a DNA-binding site located in the center region, and an amino-terminal domain
however, evidence is emerging that increased cellular GSSG accumulation may be of equal, if not greater, importance in regulating oxidative stress-triggered detrimental effects