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Thus, impaired oxidative metabolism results in decreased energy production, increased cortical excitability, and CSD, which in turn causes migraines when mitochondrial damage or dysfunction occurs in the brain

These IPGs serve as second messengers, facilitating downstream activation of IRS, PI3K/Akt pathways, and ultimately promoting glucose uptake and metabolism (135)

Metab Syndr Relat Disord

[DOI] [PubMed] [Google Scholar] 172.Xue M.Z., Rabbani N., Thornalley P.J

Some people benefit from weekly or biweekly injections during high-stress periods, frequent travel, or when recovering from illness