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Myth 4: Natural peptides like Ipamorelin have no side effects. Ipamorelin can elevate prolactin and cortisol at high doses, and any GH secretagogue can contribute to insulin resistance over time
However, development was discontinued in 2007 after the largest Phase IIb trial failed to demonstrate statistically significant weight loss compared to placebo
They range from sports injuries to local wounds with systemic inflammation, and from surgery recovery to fibromyalgia, neuroprotection, and reduced scarring after a heart attack
Important: BPC-157 is an investigational synthetic peptide compound
If the goal is body recomposition (simultaneous fat loss and muscle gain), these peptides work best in maintenance-calorie or slight-deficit conditions where insulin remains moderate and training stimulus drives nutrient partitioning toward muscle protein synthesis
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