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( Comment: Many commenters support our proposal to emphasize the Safety of Care measure group within the Overall Hospital Quality Star Rating methodology utilizing a two-stage approach, which would implement a 4-star cap in CY 2026 for hospitals in the lowest quartile of Safety of Care measure group performance (and with at least three Safety of Care measures), followed by a uniform 1-star reduction for hospitals in the lowest quartile of Safety of Care measure group performance (and with at least three Safety of Care measures) beginning in CY 2027

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The reverse LC-MS/MS response curve ( y = 1.0088 x 0.014, R 2 = 0.9999) was linear in molar ratios between 0.043 and 8.65 with Y -axis being peak area ratio [ A ([ 15 N 13 ]-CNCbl)/ A (CNCbl)] and X -axis being the molar ratio [n([ 15 N 13 ]-CNCbl)/n(CNCbl)]