The reduction of cardiovascular events is not only related to anti-diabetic properties, but also to pleotropic effects leading to the reduction of the residual cardiovascular risk, that has been defined as the risk of progression of CV events (MACE or HF) that remains after the optimal glycaemic control in T2DM patients, and it seems to be related to meta-inflammation, defined as a low-grade chronic and sterile inflammatory status
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Images were analysed using ImageJ where the background was subtracted using a rolling ball and a default threshold (Li) was used to detect both GFAP and Iba1 staining
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You may need a lower dose or need to stop taking the medicine for a short period or for good
GLP-1RA Cardiovascular Disease Outcomes Starting in 2008, the FDA began requiring all medications indicated for treatment of type 2 diabetes to evaluate cardiovascular risk reduction [45]
