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A few more serious side effects, like pancreatitis and thyroid C-cell tumors, did appear in some trials, but more testing is needed

doi: 10.1016/S0140-6736(19)31149-3 14 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al

Vargas EJ, Rizk M, Gomez-Villa J, Edwards PK, Jaruvongvanich V, Storm AC, et al

As GLP-1RAs can suppress thirst, patients should be counselled to maintain fluid intake to prevent dehydration and acute kidney injury

Shared mechanistic pathways of glucagon signalling: Unlocking its potential for treating obesity, metabolic dysfunction-associated steatotic liver disease, and other cardio-kidney-metabolic conditions