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In January 2017 an expert panel sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) issued guidelines that recommend early introduction of peanut-containing foods to infants
Metabolic syndrome in polycystic ovary syndrome
Loomba R, Hartman ML, Lawitz EJ, Vuppalanchi R, Boursier J, Bugianesi E, Yoneda M, Behling C, Cummings OW, Tang Y, Brouwers B, Robins DA, Nikooie A, Bunck MC, Haupt A, Sanyal AJ
Novo Nordisk is testing an IL6 inhibitor, Ziltivekimab, which cut hsCRP levels by ~80-90% in the phase 2 trial: The phase 3 trial is measuring the hard outcomes: cardiovascular death, myocardial infarction, or stroke, in people with established cardiovascular disease, chronic kidney disease, and persistent inflammation
This mirrors studies in transplant and non-transplant populations where increases of 510 MELD-3 points over weeks to months substantially increase short-term mortality risk (D'Amico, 2005)
They are just at different points on a trajectory of progression where the body may no longer be able to compensate as well and require drugs (prediabetes vs
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