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The angiogenic action appears tied to T4s actin-binding motif: Philp et al., FASEB J 2003 demonstrated that this seven-residue site is essential for promoting endothelial migration and vessel formation

Each component of the total RVU is adjusted by a geographic practice cost index, and the total is multiplied by a conversion factor (CF), yielding the monetary value of services provided

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The selective mechanism that avoids systemic hormonal disruption suggests potential for extended use compared to interventions that create metabolic or endocrine imbalances requiring periodic breaks

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