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Senolytic agents include natural compounds such as quercetin 13 or fisetin 14 , -galactosidase-activated nanoparticles and prodrugs 15,16,17 or compounds that target different vulnerabilities of senescent cells, such as HSP90 inhibitors 18 , cardiac glycosides 19,20 or NMT inhibitors 21

Research demonstrates DSIP significantly enhances sleep quality, particularly slow-wave deep sleep, while reducing sleep latency without sedative effects

This compound has gained attention in integrative and performance medicine for its role in modulating nicotinamide metabolism , which can influence NAD levels, insulin sensitivity, energy expenditure, and adipogenesis

In clinical trials, the weight loss percentages varied significantly depending on the dosage

Future research is required to fill current knowledge gaps using advanced technologies

Molecular aspects of medicine , 30 (1-2), 112