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Commonly prescribed GLP-1 agonists in the UK include: Semaglutide (Ozempic, Wegovy, Rybelsus [oral formulation for diabetes]) Dulaglutide (Trulicity) Liraglutide (Victoza, Saxenda) Exenatide (Byetta, Bydureon) - availability may vary Whilst initially licensed for glycaemic control, certain GLP-1 medications have received regulatory approval for weight management in adults with obesity or overweight with weight-related comorbidities

This treatment is not for anyone who has chronic kidney disease or whose creatinine levels exceed 2.5mg/dl

Regensteiner JG, Golden S, Huebschmann AG et al (2015) Sex differences in the cardiovascular consequences of diabetes mellitus: a Scientific Statement From the American Heart Association

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Likewise, liraglutide 1.8 and 3.0 mg were associated with similar reductions in total and incremental insulin and C-peptide AUCs in the first hour, including reductions in insulin and C-peptide iAUC 060 min of 20% compared with placebo (Table 2)

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