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Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase

To overcome barriers specific to solid tumors, He et al

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In addition, activation of cyclin-dependent kinase CDK11p58 reduces VDR half-life via ubiquitin-mediated degradation, further weakening VDRs transcriptional activity (19)

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