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If you experience persistent or troublesome side effects, contact your healthcare team who may recommend a temporary dose reduction, slower titration, or alternative management strategies

The mechanism involves the suppression of pro-inflammatory chemokine (C-C motif) ligand 20 (CCL20), which is of significant importance in the Th17 immune response, as well as IL-33, which is a key cytokine associated with Th2 immune responses [224]

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