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Disabling CBP/p300-binding to NRF2 broadly attenuated NRF2 transcriptional activity resulting in an altered metabolic (depletion of glutathione) and lipidomic (specific depletion of triglycerides) cellular landscape

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controlled data absent Common Model Organisms Both peptides have been studied across multiple species: Rats Primary research model (Wistar, Sprague-Dawley strains)

However, such data is not available for motor neuron disease

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