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In both cases, these medications are intended to be used long-term in combination with lifestyle interventions to support overall wellbeing

Step 1: identify your primary goal What matters most to you

This gives you a clear reference point for the 28-day post-puncture limit

A popular dual agonist, tirzepatide (Mounjaro), activates both GLP-1R and GIPR, producing synergistic effects on insulin secretion, appetite suppression, and weight reduction (Table 1)

One notable benefit is the improvement in heart health, achieved by reducing excess weight, which in turn eases the strain on arteries and reduces stress on the heart

For people with hemophilia who are also managing type 2 diabetes or obesity, these drugs may be an appealing option