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Dietary copper is usually adequate, and excess copper supplementation can be harmful

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The effectiveness of the inhibitor, combined with the lack of toxicity, makes inhibition of aspartate aminotransferase a potentially successful chemotherapeutic target

Down-regulation of SARM1 and TRAF6 reduce the level of PINK1 and then recruits Parkin to the impaired mitochondria, indicating that SARM1 plays a crucial role in mitophagy via modulating PINK1