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0.25 mg, 0.50 mg, 1.0 mg, 1.7 mg, 2.4 mg for Wegovy)

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Across the PIONEER trials, the most common adverse effects of oral semaglutide were related to the gastrointestinal tract, similar to the injectable GLP-1R agonists, and manifested as: vomiting, diarrhea and nausea (Seidu et al., 2021)

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