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[13] Use of ubiquinol supplements may be a useful intervention for FMS, especially given that meta-analysis of CoQ10 supplementation studies also support its use to improve the process of inflammatory state by lowering proinflammatory cytokines

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It is designed to selectively disrupt the FOXO4-p53 interaction in senescent cells, enabling their targeted clearance while sparing healthy cells in preclinical models

As the next phase of this research, more sophisticated in vivo models, incorporating chronic injury paradigms, long-term follow-ups, and genetic or pharmacological modifications of inflammatory pathways, will be critical to substantiate the translational potential of this approach

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In practical terms that means deeper sleep, better recovery, improved body composition, and over months, meaningful shifts in lean muscle, fat distribution, skin quality, and overall steady-state energy