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This overlap can intensify common side effects associated with GLP-1 receptor agonists, including nausea, vomiting, diarrhoea, abdominal discomfort, and constipation

This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients